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Frontiers | Early identification of hERG liability in drug discovery programs by automated patch clamp
Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia | PLOS ONE
Analysis of a New High Throughput Screening Detection Technology for Rapid hERG Safety Testing using a Fluorescence Polarization
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Novel intramolecular photoinduced electron transfer-based probe for the Human Ether-a-go-go-Related Gene (hERG) potassium channel - Analyst (RSC Publishing) DOI:10.1039/C5AN01974E
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Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay | Acta Pharmacologica Sinica
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Biomimetic membrane platform containing hERG potassium channel and its application to drug screening - Analyst (RSC Publishing) DOI:10.1039/C3AN36159D
Analysis of a New High Throughput Screening Detection Technology for Rapid hERG Safety Testing using a Fluorescence Polarization
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A structure-based computational workflow to predict liability and binding modes of small molecules to hERG | Scientific Reports
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